{
  "target": "dynorphin_a",
  "binder_lengths": [
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    65,
    75
  ],
  "crop_fasta_sequence": [
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    13
  ],
  "number_of_final_designs": 5,
  "max_trajectories": 150,
  "weights_com_distance": 0.1,
  "losses": {
    "com_distance": {
      "params": {
        "radius_ratio": 0.7
      }
    }
  },
  "min_plddt_refine": 0.65,
  "min_iptm_anneal": 0.5,
  "min_iptm_harden": 0.5,
  "min_plddt_mutate": 0.65,
  "min_iptm_mutate": 0.5,
  "min_iptm_final": 0.5,
  "min_monomer_plddt_final": 0.7,
  "project_folder": "results/dynorphin_idr",
  "aa_bias": {
    "C": 0
  }
}