{
  "description": "A longer binder, with extended optimisation; name binder_lengths as well",
  "binder_lengths": [
    250,
    600
  ],
  "screen_steps": 100,
  "refine_steps": 50,
  "anneal_steps": 90,
  "harden_steps": 10,
  "mutate_steps": 30,
  "design_models": 3,
  "validation_model": "multimer",
  "weights_plddt_loss": 1.0,
  "weights_iptm_loss": 0.1,
  "weights_interface_contacts": 0.8,
  "weights_binder_contacts": 1.8,
  "weights_interface_pae": 0.5,
  "weights_binder_pae": 0.8,
  "weights_binder_helicity": -0.2,
  "weights_compactness": 0.1,
  "min_plddt_screen": 0.6,
  "min_plddt_refine": 0.6,
  "min_plddt_mutate": 0.6,
  "min_monomer_plddt_final": 0.6,
  "filters": {
    "Binder_RMSD": {
      "threshold": 3.5,
      "higher": false
    }
  }
}